Informatics Publishing Limited

Yogita R. Indalkar ¹, N. H. Aloorkar ¹

Affiliations
1 College of Pharmacy (D. Pharm), Degaon, Satara (MH) - 415 004, IN

Abstract

Eugenol is a chief chemical constituent of clove oil and having lots of applications. Thus development of a validated UV spectrophotometric method will always advantageous. The method was validated according to International conference on Harmonization (ICH) guidelines Q2 (R1) with respect to Accuracy, Precision, linearity and range, Ruggedness, Robustness. This method is found to be linear in range between 15-50 μg/ml presenting good correlation coefficient (0.991) showing 98.87 % accuracy.

Keywords

ICH, Accuracy, Precision, Linearity And Range, Ruggedness, Robustness.

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Yogita R. Indalkar ¹, Nayana V. Pimpodkar ¹, Anita S. Godase ¹, Puja S. Gaikwad ¹

Affiliations
1 College of Pharmacy (D.Pharm), Degaon, Satara, (MH) - 415 004, IN

Abstract

The traditional medicine system is gaining wider popularity in the present times leading to increase in its commercialization at an international level. Ayurveda can serve as an excellent template for the development of nanomedicine for human theragnostics. Nanoparticals are colloidal systems with particles verying in size from 10 nm to 100 nm. The nano formulations are reportated to have remarkable advantages over respective crude drugs preparations and conventional formulations of plant actives or extracts which includes enhancement of solubility, bioavaibility, protection from toxicity, enhancement of pharmacological activity, reduction in dose enhancement of stability, improved tissue macrophages distribution, sustained delivery and protection from physical and chemical degradation. The present study shows that traditional medicines may hold strong relevance in the emerging era of nanomedicine. Thus nano sized novel drug delivery system of herbal drugs has a potential future for enhancing the activity and overcoming problem associative with herbals.

Keywords

Herbal Drugs, Nanomedicine, Novel Drug Delivery System.

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Anita S. Godase ¹, Nayana V. Pimpodkar ², Yogita R. Indalkar ¹

Affiliations
1 College of Pharmacy (D.Pharm) Degaon, Satara, (MH) - 415, IN
2 College of Pharmacy (D.Pharm) Degaon, Satara, (MH) - 415 004, IN

Abstract

This review highlighted recent reports of antimicrobial, anticancer, ACE inhibitor, antiviral as well as anti-inflammatory activities of pyrazole. The heterocyclic compound play an important role in organic chemistry and biological chemistry for their rich functionality. It is an important pharmacore and synthesis in the field of organic chemistry and drug designing. It is vast and expanding area of chemistry because of obvious application of compounds derived from heterocyclic rings in pharmacy, medicine, agriculture, plastic, polymer and other fields. Heterocyclic compounds are widely distributed in nature. By virtue of their therapeutic properties; they could be employed in the treatment of infectious diseases. Amongst the various heterocycles, pyrazole classes of compounds play an important role in medicinal chemistry.

Keywords

Pyrazole, Photoluminescence Activity, Anti-Inflammatory Activity etc.

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Yogita R. Indalkar ¹, Nayana V. Pimpodkar ¹, Puja S. Gaikwad ¹, Anita S. Godase ¹

Affiliations
1 College of Pharmacy (D. Pharm), Degaon, Satara (MH) 415 004, IN

Abstract

Biodegradable polymers have been widely used in biomedical applications because of their known biocompatibility and biodegradability. Degradable polymeric biomaterials are preferred candidates for developing therapeutic devices such as temporary prostheses, three dimensional porous structures as scaffolds for tissue engineering and as controlled/sustained release drug delivery vehicles. Biodegradable materials are used in packaging, agriculture, medicine and other areas. In the biomedical area, polymers are generally used as implants and are expected to perform long term service. These improvements contribute to make medical treatment more efficient and to minimize side effects and other types of inconveniences for patients. The following review presents an overview of the different biodegradable polymers and their applications.

Keywords

Biodegradable, Biocompatibility, Polymers.

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Puja S. Gaikwad ¹, Nayana V. Pimpodkar ¹, Yogita R. Indalkar ¹, Anita S. Godase ¹

Affiliations
1 College of Pharmacy (D.Pharm), Degaon, Satara (MH) - 415 004, IN

Abstract

Oral cavity cancer, or just oral cancer, is cancer that start in the mouth (also called the oral cavity). Oropharyngeal cancer starts in the oropharynx, which is the part of the throat just behind the mouth. The major causes of oral cancer include tobacco use, areca nut chewing and heavy alcohol drinking; avoiding these can prevent the disease. Preceded by precancerous lesions, early oral cancers present as small painless ulcers or growths that can be detected, by careful physical examination, and if effectively treated by the physician. Prevention, early detection and treatment are effective interventions to reduce the worldwide burden of oral cancer. Early detection of oral cancer needs more than just understanding of the signs and symptoms of disease. The process must be managed effectively and handled sensitively. Every member of the dental team has a part to play and protocols should be developed for effective delivery of Dental and healthcare professionals have a crucial role to play in raising awareness of the dangers to oral health associated with smoking and the use of smokeless tobacco. Early detection of oral cancer needs more than just understanding of the signs and symptoms of disease. In its early stages, oral cancer can be treated in up to 90% of cases.

Keywords

Oral Cancer, Early Detection, Prevention, Treatment.

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